Cat Flea & Tick Control Comparison Chart

Cat Products /
Manufacturer /
Frequency Administration
Kill Adult Fleas Kills Flea Eggs Kills Ticks Repels Mosquitoes Kills Lice Repels Flies Earliest
Age for Use
Active Ingredient
Cat Products: Advantage II for Cats
Manufacturer: Bayer
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: Yes Kills Ticks: No Repels Mosquitoes: No Kills Lice: No

Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Imidacloprid + Pyriproxyfen
Cat Products: Bio Spot Spot On for Cats
Manufacturer: Farnam
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: Yes Kills Ticks: Yes Repels Mosquitoes: Yes Kills Lice: No Repels Flies: No Earliest
Age for Use:
12 weeks
Active Ingredient: Etofenprox + (s)Methoprene
Cat Products: FiproGuard
Manufacturer: Sentry/ Sergeant's
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: No Kills Ticks: Yes Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil
Cat Products: FiproGuard Max
Manufacturer: Sentry/ Sergeant's
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: No Kills Ticks: Yes Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil
Cat Products: Frontline Plus
Manufacturer: Merial
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: Yes Kills Ticks: Yes Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil + (s)Methoprene
Cat Products: Frontline Top Spot
Manufacturer: Merial
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: No Kills Ticks: Yes Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Finopril
Cat Products: Natural Defense
Squeeze-On

Manufacturer: Sentry/ Sergeant's
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: No Kills Ticks: Yes Repels Mosquitoes: Yes Kills Lice: No Repels Flies: No Earliest
Age for Use:
12 weeks
Active Ingredient: Natural Botanical Oils
Cat Products: PetArmor
(compares to FiproGuard)
Manufacturer: FidoPharm
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: No Kills Ticks: Yes Kills Lice: No Repels Mosquitoes: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil
Cat Products: Pronyl OTC Max
(compares to FiproGuard)
Manufacturer: Sergeant's
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: No Kills Ticks: Yes Kills Lice: No Repels Mosquitoes: Yes Repels Flies: No Earliest
Age for Use:
12 weeks
Active Ingredient: Fipronil + Etofenprox
Cat Products: SpectraSure Plus
(compares to FiproGuard)
Manufacturer: Durvet
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: No Kills Ticks: Yes Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
12 weeks
Active Ingredient: Fipronil + Etofenprox
Cat Products: TriForce Feline Squeeze-On
Manufacturer: AgriLabs
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: Yes Kills Ticks: Yes Repels Mosquitoes: Yes Kills Lice: No Repels Flies: No Earliest
Age for Use:
12 weeks
Active Ingredient: Etofenprox +
Pyripoxyfen (Nylar)
Cat Products: Vectra
Manufacturer: Ceva
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: No Kills Ticks: No Repels Mosquitoes: No Kills Lice: No Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Dinotefuran + Pyriproxyfen
Cat Products: EasySpot
(compares to FiproGuard)
Manufacturer: Novartis
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs: No Kills Ticks: Yes Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil

For more flea control information read: Control Fleas in 3 Easy Steps