(Merial) Protection against mastitis caused by E. coli and the effects of endotoxemia due to E. coli and salmonella in cattle. Recommended at 7th month of pregnancy or at dry off. Give 2 ml IM or SQ. Repeat 1 to 3 weeks before calving and with 2 doses annually. For herd vaccination against endotoxemia, give 2 ml IM or SQ. Repeat in 2 to 4 weeks and with 2 doses annually.