(Merck) Zuprevo 18% contains tildipirosin, a macrolide antibiotic. For treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni, and for control of respiratory disease in cattle at high risk of developing BRD associated with M. haemolytica, P. multocida and H. somni. For use in beef and non-lactating dairy cattle. Each ml of Zuprevo contains 180 mg tildipirosin. A single dose of Zuprevo concentrates in the lungs for 28 days and in bronchial fluid for 21 days to treat and control BRD. Administer one dose, 1 ml per 100 lbs. SQ in the neck, not to exceed 10 ml per injection site. Zuprevo is not for use in female dairy cattle 20 months of age or older, or in calves to be processed for veal. 180 mg/ml Tildipirosin.