(Novartis Animal Health) Percorten-V is used as replacement therapy for the mineralocorticoid deficit in dogs with primary adrenocortical insufficiency (Addison’s Disease). Canine Addison's Disease (hypoadrenocorticism) is a condition in which a dog's adrenal glands aren't working properly. Adrenal glands produce chemicals and hormones that help regulate many bodily functions such as metabolism, blood pressure and stress response. Percorten-V contains 25mg/ml desoxycorticosterone pivalate, which is recognized as having the same qualitative effects as the natural hormone aldosterone. The beginning dose may be recommended at 1 mg per pound of body weight every 25 days. Percorten-V increases the rate of sodium absorption and enhances potassium excretion. Percorten-V also increases extracellular fluid volume, which expands blood volume and improves the venous return to the heart and cardiac output. This effect prevents the life-threatening hypotensive shock and prerenal azotemia observed in animals suffering from hypoadrenocorticism. Desoxycorticosterone pivalate.