(Pro Labs) Univac10 includes protection against coronavirus, canine distemper, adenovirus type 2, hepatitis, parainfluenza, updated parvovirus Type 2b, and 4 strains of Lepto (L. canicola, L. grippotyphosa, L. icterohaemorrhagiae, and L. pomona,). Modified live plus killed coronavirus. Give 1 ml SQ. Beginning at 6 weeks of age give every 2 to 3 weeks until 16 weeks of age. If primary vaccination is given after 12 weeks of age, give 2 doses, 2-3 weeks apart. Annual revaccination with a single dose is recommended. Not for pregnant bitches. Univac 10 requires mixing. Consult with your veterinarian about the advisability of vaccinating for lepto.