(Bayer) K9 Advantix II is a topical for the prevention and treatment of ticks, fleas, mosquitoes, biting flies and lice on dogs and puppies over 7 weeks old. K9 Advantix II contains Imidacloprid and Permethrin, plus insect growth regulator Pyriproxyfen. Repels and kills ticks for up to four weeks. Repels and kills fleas of all life stages. Kills fleas within 12 hours of application and prevents further flea infestations for a month. Prevents development of fleas, flea eggs, pupae and larvae for a month. Repels and kills mosquitoes for up to four weeks. Repels and prevents blood feeding by biting flies. Kills chewing lice. Waterproof.