(Generic) Methylprednisolone is an anti-inflammatory steroid for use in dogs and cats. Methylprednisolone Tablets may be used in the treatment of allergies, skin-related conditions, ocular conditions, osteoarthritis, and certain autoimmune diseases. The typical total daily dosage for dogs and cats is: 2 mg for 5-15 lbs. body weight; 2 to 4 mg for 15-40 lbs.; 4 to 8 mg for 40-80 lbs. The total daily dosage should be given in divided doses, 6 to 10 hours apart.