(Zoetis Animal Health) Vanguard Plus 5 L4 CV is a 7-way + coronavirus Modified live plus killed coronavirus. For protection against canine distemper, adenovirus type 2 (and hepatitis), parainfluenza, parvovirus, 4 strains of Lepto and coronavirus. For dogs 6 weeks of age or older. Give 1 ml Vanguard Plus 5 L4 CV IM or SQ. Give 3 doses, each 3 weeks apart. If primary vaccination is given after 9 weeks of age, give 2 doses, 3 weeks apart. Annual revaccination with a single dose is recommended. Not for pregnant bitches. Requires mixing. Order syringes separately.