(Zoetis Animal Health) Predef 2X is a potent corticosteroid. It is indicated in certain situations requiring glucocorticoid, anti-inflammatory, and/or supportive effect in cattle, swine, and horses. May be used in the treatment of bovine ketosis, musculoskeletal conditions, allergic reactions, milk fever, infections, shock, dystocia, retained placenta, inflammatory ocular conditions, and other conditions. Predef 2X contains 2 mg of isoflupredone acetate per ml suspension. Predef 2X is administered by deep intramuscular injection for systemic effect, or into joint cavity, tendon sheath, or bursa for local effect.