(Zoetis Animal Health) 7-way Modified live. Vanguard Plus 5 L4 is for protection against canine distemper, adenovirus type 2 (and hepatitis), parainfluenza, parvovirus and 4 strains of Lepto. For dogs 6 weeks of age or older. Give 1 ml Vanguard Plus 5 L4 IM or SQ. Give 3 doses, each 3 weeks apart. If primary vaccination is given after 9 weeks of age, give 2 doses, 3 weeks apart. Annual revaccination with a single dose is recommended. Not for pregnant bitches. Requires mixing. Order syringes separately.