(Bimeda) PrimeMune is a 5-way modified live canine vaccine. PrimeMune is used for prevention of disease caused by canine distemper, adenovirus type 2 (and hepatitis) and as an aid in the prevention of disease caused by parainfluenza and parvovirus. PrimeMune is for dogs 6 weeks of age or older. Give 1 ml SQ. Give PrimeMune beginning as early as 6 weeks of age. Revaccinate every 3 to 4 weeks until 12 weeks of age. A minimum of two doses is required for primary immunization. Annual revaccination with a single dose is recommended. Not for pregnant bitches. Requires mixing. Order syringes separately.