The extra ingredients in Cosamin® ASU have been shown to work better than the combination of glucosamine and chondroitin alone.
Cosamin® ASU is designed for active people with joint discomfort. The makers of Cosamin DS have taken their #1 orthopedic surgeon and rheumatologist recommended joint product and added avocado/soybean unsaponifiables (ASU) to make a product that is more effective than the additive effects of all three ingredients. To this they have added the antioxidant green tea extract to help with joint and overall body defenses. Start out with 4 capsules per day until the desired effect is noticed, then gradually reduce to a maintenance dose.
What is ASU?
ASU stands for avocado/soybean unsaponifiables, derived from avocados and soybeans and used for joint health. ASU works with the glucosamine and chondroitin sulfate in Cosamin ASU. Cartilage cell studies have shown ASU to be synergistic with the glucosamine; synergy means that the compounds together produce a greater than additive effect. Studies on joint tissue cells have also shown that ASU reduces the expression of inflammatory markers. These markers are associated with joint discomfort and cartilage breakdown. While glucosamine and chondroitin sulfate also do this, the combination of glucosamine and chondroitin sulfate plus ASU has been shown in cell research to be even better.
Cosamin ASU also contains decaffeinated green tea for antioxidant health benefit effects. These effects have a positive impact on cartilage as well as on overall body defenses.
*In laboratory cell culture studies of inflammatory markers associated with joint discomfort and cartilage breakdown, it was found that the combination of ASU (avocado/soybean unsaponifiables) + glucosamine + chondroitin sulfate was better than the combination of glucosamine + chondroitin sulfate in reducing these markers.
What role do the glucosamine hydrochloride and chondroitin sulfate play?
The combination of the trademarked FCHG49 glucosamine and TRH122 sodium chondroitin sulfate supports cartilage production and inhibits enzymes in the joints that break down cartilage. Laboratory and clinical research has demonstrated that glucosamine hydrochloride and chondroitin sulfate can help reduce joint pain. In addition, these ingredients together have been shown in laboratory studies to protect joint cartilage better than either ingredient alone. A greater than additive effect, known as a “synergistic” effect, on cartilage cells was seen using glucosamine and chondroitin sulfate together.
What should I look for when taking Cosamin ASU?
Individual improvement on Cosamin ASU can range from gradual to dramatic, with some individuals responding sooner than others. Cosamin ASU is a supplement providing key components to maintain your joint health; therefore, it works gradually. You should observe gradual changes in your comfort level. Give yourself time to respond. Look for subtle changes initially, such as an easier time going up and down stairs or getting out of a chair or bathtub and more comfort in daily activities, such as walking or any activity using your hands, knees, hips or back.
Initial dosage: Take 4 capsules per day. Capsules may be taken all at once or divided with meals throughout the day. It may take up to 6 weeks before the initial effect of Cosamin ASU is noted.
Maintenance: Once desired effect is noticed, you may gradually reduce the number of capsules to maintain comfort level.
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