(Veterinary Products Labs) Duralactin Canine Joint Plus Soft Chews help maintain healthy cartilage and joint function while managing inflammation. Contains MicroLactin, a patented dried milk protein concentrate derived from hyper immunized cows that contain factors that appear to block cytokines and inhibit neutrophil participation in the inflammatory response. Its mechanism of action is not shared by any known drug and it is not a COX-1 or COX-2 inhibitor. Each Duralactin Canine Joint Plus Soft Chew contains 500 mg MicroLactin, 250 mg glucosamine HCl, 200 mg MSM, 5 mg manganese and Omega-3 fatty acids. Give 1 Soft Chew per 40 lbs. twice daily.