Dog Flea & Tick Control Comparison Chart

Dog Products /
Manufacturer /
Frequency Administration
Kills Adult Fleas Kills Flea Eggs/Larvae Kills Ticks Kills/Repels Mosquitoes Kills Lice Repels Flies Earliest
Age for Use
Active Ingredient
Dog Products: Advantage II for Dogs
Manufacturer: Bayer
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: Yes Kills Ticks: No Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
7 weeks
Active Ingredient: Imidacloprid +
Pyriproxyfen
Dog Products: Ecto-Advance (compares to Fiproguard)
Manufacturer: Vedco
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil
Dog Products: Effipro (compares to Fiproguard)
Manufacturer: Virbac
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil
Dog Products: Effitix
Manufacturer: Virbac
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: Yes Kills Lice: Yes Repels Flies: Yes Earliest
Age for Use:
12 week
Active Ingredient: Fipronil 6.01% +
Permethrin 44.8%
Dog Products: FiproGuard
Manufacturer: Sentry/Sergeant's
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Finopril
Dog Products: Frontline Plus
Manufacturer: Merial
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: Yes Kills Ticks: Yes Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil +
(s)Methoprene
Dog Products: Frontline Top Spot
Manufacturer: Merial
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil
Dog Products: Happy Jack DuraSpot (compares to Liberty 50)
Manufacturer: Happy Jack
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: Yes Kills Ticks: Yes Kills/Repels Mosquitoes: Yes Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
12 weeks
Active Ingredient: Permethrin +
Pyriproxyfen (Nylar)
Dog Products: K9 Advantix II
Manufacturer: Bayer
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: Yes Kills Ticks: Yes Kills/>Repels Mosquitoes: Yes Kills Lice: Yes Repels Flies: Yes Earliest
Age for Use:
7 weeks
Active Ingredient: Imidacloprid +
Permethrin + Pyriproxyfen (Nylar)
Dog Products: Liberty 50 Spot-On
for Dogs

Manufacturer: Star Horse Products
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: Yes Kills Ticks: Yes Kills/Repels Mosquitoes: Yes Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
12 weeks
Active Ingredient: Permethrin +
Pyriproxyfen (Nylar)
Dog Products: Natural Defense
Squeeze-On

Manufacturer: Sentry/Sergeant's
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: Yes Kills Lice: No Repels Flies: No Earliest
Age for Use:
12 weeks
Active Ingredient: Natural Botanical Oils
Dog Products: OmniTrol(compares to Liberty 50)
Manufacturer: Vedco
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: Yes Kills Ticks: Yes Kills/Repels Mosquitoes: Yes Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
12 weeks
Active Ingredient: Permethrin +
Pyriproxyfen (Nylar)
Dog Products: ParaStar (compares to FiproGuard)
Manufacturer: Novartis
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: >No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil
Dog Products: Pet Armor (compares to FiproGuard)
Manufacturer: FidoPharm
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil
Dog Products: Pet Armor Plus (compares to Frontline Plus)
Manufacturer: FidoPharm
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: Yes Kills Ticks: Yes Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil +
(s)Methoprene
Dog Products: Pronyl OTC Max (compares to FiproGuard Max)
Manufacturer: Seargent's
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
12 weeks
Active Ingredient: Finopril +
Cyphenothrin
Dog Products: SpectraSure (compares to FiproGuard)
Manufacturer: Durvet
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
8 weeks
Active Ingredient: Fipronil
Dog Products: SpectraSure Plus (compares to FiproGuard Max)
Manufacturer: Durvet
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: No Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
12 weeks
Active Ingredient: Fipronil +
Cyphenothrin
Dog Products: Vectra 3D
Manufacturer: Ceva
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: No Kills Ticks: Yes Kills/Repels Mosquitoes: Yes Kills Lice: Yes Repels Flies: No Earliest
Age for Use:
7 weeks
Active Ingredient: Dinotefuran +
Pyriproxyfen + Permethrin
Dog Products: Vet-Kem Ovitrol X-Tend
Manufacturer: VPL
Frequency Administration: monthly topical
Kills Adult Fleas: Yes Kills Flea Eggs/Larvae: Yes Kills Ticks: Yes Kills/Repels Mosquitoes: Yes Kills Lice: No Repels Flies: >No Earliest
Age for Use:
6 months
Active Ingredient: Etofenprox +
(s)Methoprene + piperonyl

For more flea control information read: Control Fleas in 3 Easy Steps

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