Trifexis for Dogs

Trifexis (spinosad + milbemycin oxime) Heartworm and Flea Prevention Chewable Tablets for Dogs is indicated for the prevention of heartworm disease; kills fleas; prevents and treats flea infestations; treats and controls adult hookworm, adult roundworm and adult whipworm infections. Trifexis for Dogs can be used in dogs and puppies at least 8 weeks of age and at least 5 pounds. Trifexis is given orally once a month with food for maximum effectiveness.

* spinosad + milbemycin oxime
* prevention of heartworm disease
* kills fleas & prevents infestations
* treatment & control of adult hookworm, roundworm & whipworm infections
* once a month
* chewable tablets


Heartworm Prevention: Trifexis should be administered at monthly intervals beginning within 1 month of the dog’s first seasonal exposure and continuing until at least 3 months after the dog’s last seasonal exposure to mosquitoes. Trifexis may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of Trifexis should be given within a month of the last dose of the former medication.

Flea Treatment and Prevention: Treatment with Trifexis may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with Trifexis should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product.

Intestinal Nematode Treatment and Control: Trifexis also provides treatment and control of roundworms (T. canis, T. leonine,) hookworms (A. caninum,) and whipworms (T. vulpis). Dogs may be exposed to and can become infected with roundworms, whipworms, and hookworms throughout the year, regardless of season or climate.

• How to Order Prescription Medications
• Veterinarian Information

Please note that this item requires a veterinarian's prescription.

Three convenient ways to do that are:

1. Let us contact your veterinarian for prescription authorization.
2. Your veterinarian can contact us by fax/phone.
3. You can mail us the original written prescription.

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• Label Information
• Dog Heartworm Prevention Products Comparison Chart
• FAQ: About Heartworms and Heartworm Disease
• How to Protect Pets from Heartworms: 3 Steps
• How to Dispose of Unused Medicines
• Other products by Elanco Animal Health